Ebola Transmission – Understanding and Preparing for an Outbreak

Ebola Transmission

Ebola outbreaks are believed to start through a natural reservoir, such as a fruit bat. Other animals may feed on fruit dropped by the bat, or the bats themselves. It is believed that humans are infected through handling and consuming bush meat.

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When an infection occurs in a human, Ebola can be spread in several ways. According to the CDC, Ebola is spread through:

  • Direct contact: Direct contact (through broken skin or the nose, mouth, or eyes) with blood or other bodily fluids (such as saliva, urine, sweat, semen, breast milk, or feces) of the infected person.
  •  Animals: Natural reservoirs or carrier animals.
  • Objects (fomites) that have been come in contact with the infected person:

Ebola can survive on fomites for various lengths of time, depending on environmental conditions. Laboratory experiments have shown that the virus can survive in infected tissue on surfaces for over 50 days at a temperature of 4oC (-15oF). In other experiments, the virus was able to survive in the dark for hours at temperatures of 20oC (68oF) and 30%-40% relative humidity. The amount of detectable virus was reduced to 37% of the original amount after 15.4 hours.

  • Airborne droplets (Not Confirmed by Authorities):

The CDC makes no mention of Ebola transmission through airborne droplets in humans. Because of the severity of the current outbreak, however, Ebola transmission through airborne droplets seems like a possible explanation. Note that the author says airborne droplets and not simply airborne. There is a huge difference. Airborne implies that a disease can be spread through the inhalation of tiny, dry particles that remained suspended in the air for long a period of time. These particles could also theoretically be transferred through air currents. Ebola is not airborne in this sense. The rate of infection is much too low. If Ebola was truly airborne, it should spread at a rate similar to tuberculosis, chickenpox or measles. One person with measles, on average, infects 12 to 18 people. The current Ebola outbreak appears to spread, on average, to one to two people. This value is known as the Basic Reproductive Number, R0. The following is a chart of the Basic Reproductive Numbers for various diseases.

Ebola Transmission

Airborne droplets, however, is a different story. Airborne droplets are relatively large (when compared to the dry particles that are suspended in the air by an airborne disease), wet particles, propelled through the air by way of coughing, sneezing or violent vomiting, that land on walls, floors, or other people. It is entirely possible that Ebola is spread via airborne droplets. The CDC still denies this. The WHO downplays the probability. Other experts, especially those who are independent of governmental organizations, are not as quick to dismiss this.

Despite CDC claims that droplet transmission is not possible, it has been shown that VHFs have an infectious dose of 1 to 10 organisms by airborne droplets in non-human primates.

  1. Source: Franz, D. R., Jahrling, P. B., Friedlander, A. M., McClain, D. J., Hoover, D. L., Bryne, W. R., Pavlin, J. A., Christopher, G. W., & Eitzen, E. M. (1997). Clinical recognition and management of patients exposed to biological warfare agents. Jama, 278(5), 399-411.)

Additionally, laboratories have been able to demonstrate that primates exposed to airborne droplets from pigs have become infected.

  1. Source: Twenhafel, N. A., Mattix, M. E., Johnson, J. C., Robinson, C. G., Pratt, W. D., Cashman, K. A., Wahl-Jensen, V., Terry, C., Olinger, G. G., Hensley, L. E., & Honko, A. N. (2012). Pathology of experimental aerosol Zaire ebolavirus infection in rhesus macaques. Veterinary Pathology Online, 0300985812469636.
  2. Source: Mwanatambwe, M., Yamada, N., Arai, S., Shimizu-Suganuma, M., Shichinohe, K., & Asano, G. (2001). Ebola hemorrhagic fever (EHF): mechanism of transmission and pathogenicity. Journal of Nippon Medical School.68 (5), 370-375.
  3. Source: Plague. (2004). In R. G. Darling, & J. B. Woods (Eds.), USAMRIID’s Medical Management of Biological Casualties Handbook (5th ed., pp. 40-44). Fort Detrick M.D.: USAMRIID.
  4. Source: Reed, D. S., Lackemeyer, M. G., Garza, N. L., Sullivan, L. J., & Nichols, D. K. (2011). Aerosol exposure to Zaire ebolavirus in three nonhuman primate species: differences in disease course and clinical pathology. Microbes and Infection, 13(11), 930-936.
  5. Source: Feigin, R. D. (Ed.). (2004). Textbook of Pediatric Infectious Diseases (5th Ed.). Philadelphia, USA: Elsevier, Inc.

 

  • Aerosol Transmissibles (Not Confirmed by Authorities): According to The Center for Infectious Disease Research and Policy (CIDRAP), “We believe there is scientific and epidemiologic evidence that Ebola virus has the potential to be transmitted via infectious aerosol particles both near and at a distance from infected patients, which means that healthcare workers should be wearing respirators, not facemasks.”

They continue, “Modern research, using more sensitive instruments and analytic methods, has shown that aerosols emitted from the respiratory tract contain a wide distribution of particle sizes—including many that are small enough to be inhaled. Thus, both small and large particles will be present near an infectious person. The chance of large droplets reaching the facial mucous membranes is quite small, as the nasal openings are small and shielded by their external and internal structure. Although close contact may permit large-droplet exposure, it also maximizes the possibility of aerosol inhalation. As noted by early aerobiologists, liquid in a spray aerosol, such as that generated during coughing or sneezing, will quickly evaporate, which increases the concentration of small particles in the aerosol. Because evaporation occurs in milliseconds, many of these particles are likely to be found near the infectious person. The current paradigm also assumes that only “small” particles (less than 5 micrometers [mcm]) can be inhaled and deposited in the respiratory tract. This is not true. Particles as large as 100 mcm (and perhaps even larger) can be inhaled into the mouth and nose. Larger particles are deposited in the nasal passages, pharynx, and upper regions of the lungs, while smaller particles are more likely to deposit in the lower, alveolar regions. And for many pathogens, infection is possible regardless of the particle size or deposition site.”

CIDRAP concludes:

“To summarize, for the following reasons we believe that Ebola could be an opportunistic aerosol-transmissible disease requiring adequate respiratory protection:

  • Patients and procedures generate aerosols, and Ebola virus remains viable in aerosols for up to 90 minutes.
  • All sizes of aerosol particles are easily inhaled both near to and far from the patient.
  • Crowding, limited air exchange, and close interactions with patients all contribute to the probability that healthcare workers will be exposed to high concentrations of very toxic infectious aerosols.
  • Ebola targets immune response cells found in all epithelial tissues, including in the respiratory and gastrointestinal system.
  • Experimental data support aerosols as a mode of disease transmission in non-human primates.”

The author tends towards CIDRAP’s stance. Infection through Direct Contact is certain, and airborne droplet seems likely, but aerosol transmissibles for up to 90 minutes appears possible as well.

The complete CIDRAP article (with multiple sourced studies) can be found here:

http://www.cidrap.umn.edu/news-perspective/2014/09/commentary-health-workers-need-optimal-respiratory-protection-ebola

  • Viral Shedding (Not Confirmed by Authorities): Researchers have also observed viral shedding from infected pigs via nasopharyngeal (upper portion of the pharynx, from the base of the skull to the roof of the mouth) secretions and rectal swabs.
  1. Source: Kobinger, G. P., Leung, A., Neufeld, J., Richardson, J. S., Falzarano, D., Smith, G., Tierney, K., Patel, A., & Weingartl, H. M. (2011). Replication, pathogenicity, shedding, and transmission of Zaire ebolavirus in pigs. Journal of Infectious Diseases, jir077.
  2. Source: Marsh, G. A., Haining, J., Robinson, R., Foord, A., Yamada, M., Barr, J. A., Payne, J., White, J., Yu, M., Bingham, J., Rollin, P. E., Nichol, S. T., Wang, L-F., & Middleton, D. (2011). Ebola Reston virus infection of pigs: clinical significance and transmission potential. Journal of Infectious Diseases, 204(suppl 3), S804-S809.

The author would contend that there are no studies that suggest airborne droplet, aerosolized transmissions and viral shedding in humans is possible because researchers are having a difficult time finding volunteers, with there not being a cure and all.

  • Semen: Another means of Ebola transmission worth discussing is semen. Studies have suggested that the Ebola Virus may remain transmissible through a survivor’s semen for 70 to over 90 days. Survivors should abstain from sexual contact for at least four months, or until additional research can be performed to determine a more precise period of possible infection.

Once an infected person recovers from Ebola, they can no longer spread it, other than through semen. People who recover develop antibodies that may last for at least 10 years. These antibodies may be critical in the development of a viable treatment for the virus.

There is no evidence that mosquitos or other insects can transmit Ebola. Only mammals have displayed the ability to become infected and spread the virus.

By Alex Smith

Now Available, By Alex Smith –
EBOLA:

Understanding and Preparing for an Outbreak

The 2014 West African Ebola Outbreak has spread into Europe and the United States.

The WHO admits that this crisis will get much worse before it gets better.

Are you prepared for an outbreak?

What should you do to prepare?

Ebola: Understanding and Preparing for an Outbreak, addresses these, and many more questions.

Written in a clear and concise manner, with the reader that has beginning or intermediate knowledge of the Ebola Virus and disaster preparedness in mind, this book explores the following topics:

Chapter 1: Introduction and Glossary of Terms

Chapter 2: About Ebola Transmission, Symptoms, Treatment

Chapter 3: The History of Ebola

Chapter 4: The 2014 West African Ebola Outbreak

Chapter 5: Early Stage – What to do Now

Chapter 6: Advanced Stage – Outbreaks in Your Country/Region

Chapter 7: Crisis Stage – An Epidemic in Your Area

Chapter 8: Methods of Disinfection

Chapter 9: Establishing Safe Practices (Isolation Rooms, Quarantine Areas, Cleaning Spills, etc.)

Chapter 10: Preparations (PPEs and Other Necessary Supplies)

               Other useful resources:

Blackout USA (EMP survival and preparedness guide)

Backyard Innovator (All Year Round Source Of Fresh Meat,Vegetables And Clean Drinking Water)

Conquering the coming collapse (Financial advice and preparedness )

Liberty Generator (Easy DIY to build your own off-grid free energy device)

Backyard Liberty (Easy and cheap DIY Aquaponic system to grow your organic and living food bank)

Bullet Proof Home (A Prepper’s Guide in Safeguarding a Home )

Family Self Defense (Best Self Defense Strategies For You And Your Family)

Sold Out After Crisis (Best 37 Items To Hoard For A Long Term Crisis)

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